L'ac\u00e9tate de sermor\u00e9line est un peptide synth\u00e9tique compos\u00e9 des 29 premiers acides amin\u00e9s de l'hormone de lib\u00e9ration de l'hormone de croissance (GHRH), le signal hypothalamique qui incite l'hypophyse \u00e0 lib\u00e9rer l'hormone de croissance. Ce fragment de 29 r\u00e9sidus est la s\u00e9quence la plus courte dont on a d\u00e9montr\u00e9 qu'elle porte toute l'activit\u00e9 de l'hormone native, ce qui explique pourquoi la sermor\u00e9line est devenue l'analogue de r\u00e9f\u00e9rence de la GHRH dans la litt\u00e9rature.<\/p>\n
Sermorelin acts on the GHRH receptor in the pituitary rather than supplying growth hormone directly, so the release it prompts in laboratory models keeps the body’s own pulsatile rhythm and stays under the normal feedback from somatostatin and IGF-1. That preserved regulation is the reason researchers choose it to study the growth hormone axis without overriding it.<\/p>\n
Parce qu'elle agit par le r\u00e9cepteur de la GHRH, la sermor\u00e9line est couramment \u00e9tudi\u00e9e aux c\u00f4t\u00e9s de s\u00e9cr\u00e9tagogues du r\u00e9cepteur de la ghr\u00e9line comme l'ipamor\u00e9line, qui agissent sur un r\u00e9cepteur diff\u00e9rent du m\u00eame axe. Les deux m\u00e9canismes sont compl\u00e9mentaires, et cette association traverse une grande partie de la litt\u00e9rature sur l'hormone de croissance.<\/p>\n
Les travaux publi\u00e9s sur l'ac\u00e9tate de sermor\u00e9line portent sur la signalisation de l'hormone de croissance et de l'IGF-1, la composition corporelle, l'architecture du sommeil et le d\u00e9clin de la production hypophysaire qui accompagne l'\u00e2ge. Il est fourni sous forme de sel d'ac\u00e9tate lyophilis\u00e9, \u00e0 reconstituer.<\/p>\n
Domaines de recherche courants :<\/strong> Recherche sur l'hormone de croissance<\/p>","protected":false},"featured_media":1729,"comment_status":"open","ping_status":"closed","template":"","meta":{"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","_vistara_fr_title":"Acheter de la sermor\u00e9line au Canada | Vistara Labs","_vistara_fr_desc":"Ac\u00e9tate de sermor\u00e9line, peptide de recherche, flacons lyophilis\u00e9s de 5 mg et 10 mg. Exp\u00e9di\u00e9 depuis le Canada. Usage laboratoire uniquement."},"product_brand":[],"product_cat":[18,24],"product_tag":[],"class_list":["post-1724","product","type-product","status-publish","has-post-thumbnail","product_cat-longevity","product_cat-muscle-growth","first","outofstock","shipping-taxable","purchasable","product-type-variable","entry","content-bg","loop-entry"],"_links":{"self":[{"href":"https:\/\/vistaralabs.ca\/fr\/wp-json\/wp\/v2\/product\/1724","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vistaralabs.ca\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vistaralabs.ca\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/vistaralabs.ca\/fr\/wp-json\/wp\/v2\/comments?post=1724"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vistaralabs.ca\/fr\/wp-json\/wp\/v2\/media\/1729"}],"wp:attachment":[{"href":"https:\/\/vistaralabs.ca\/fr\/wp-json\/wp\/v2\/media?parent=1724"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/vistaralabs.ca\/fr\/wp-json\/wp\/v2\/product_brand?post=1724"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vistaralabs.ca\/fr\/wp-json\/wp\/v2\/product_cat?post=1724"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vistaralabs.ca\/fr\/wp-json\/wp\/v2\/product_tag?post=1724"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Growth hormone secretion, GHRH receptor signalling, IGF-1 pathways, body composition, sleep and recovery models, endocrine ageing research.<\/p>","protected":false},"excerpt":{"rendered":"