BPC-157 is a synthetic 15-amino-acid peptide whose sequence comes from a protein found in human gastric juice, and its developers describe it as stable in that juice for more than 24 hours. It is one of the most widely studied repair peptides in laboratory and animal research, covering tendon, muscle, gut and blood-vessel models.
This reference collects what a laboratory needs to know about BPC-157 as a material: how its sequence behaves in the vial, what it dissolves in, how it is handled at the bench and what to do when an order arrives. Each section below has its own page.
Molecular reference
| Name | BPC-157 (body protection compound 157) |
|---|---|
| Also known as | Bepecin, PL-10, pentadecapeptide BPC 157 |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV) |
| Residues | 15 |
| Molecular formula | C62H98N16O22 |
| Molecular weight | 1419.5 g/mol |
| CAS number | 137525-51-0 |
Three features of that sequence explain most of its behaviour. It carries four prolines, three of them in a row at positions 3 to 5, which keep the chain from folding into the sheet structures that make peptides clump. It has no methionine, cysteine, tryptophan, histidine, asparagine or glutamine, so the oxidation and deamidation routes that limit many peptides are simply absent. And it has an aspartic acid pair at positions 10 and 11, which is the one bond chemists single out as its main slow weak point in solution (Mateescu et al., Pharmaceutics, 2026).
What it is studied for
BPC-157 was developed by a research group in Zagreb as an anti-ulcer peptide, and much of its early literature concerns the gastrointestinal tract, where it protected the stomach and gut lining across many animal injury models (Sikiric et al., Current Pharmaceutical Design, 2011). Later reviews from the same group extend this to wound healing in skin, tendon, ligament, muscle and bone models (Seiwerth et al., Frontiers in Pharmacology, 2021) and to striated, smooth and heart muscle (Staresinic et al., Biomedicines, 2022).
Independent laboratories have looked at how it works. In animal Achilles tendon explants it accelerated fibroblast outgrowth, improved cell survival under oxidative stress and increased fibroblast migration through the FAK and paxillin pathway (Chang et al., Journal of Applied Physiology, 2011). In endothelial cells and an animal hind-limb ischemia model it raised blood-vessel density and up-regulated the VEGFR2 receptor (Hsieh et al., Journal of Molecular Medicine, 2017). A formal study in two animal species measured a plasma half-life under 30 minutes and linear kinetics, with the peptide broken down into small fragments and single amino acids (He et al., Frontiers in Pharmacology, 2022).
Human research includes a knee-pain chart review in which 14 of 16 patients reported significant improvement (Lee and Padgett, Alternative Therapies in Health and Medicine, 2021). Our summaries are in BPC-157 research and the knee-pain data and BPC-157 vs TB-500.
Stability
Because its sequence lacks the residues that oxidise or deamidate, BPC-157 is unusually forgiving. Its slow route in solution is hydrolysis at the Asp10 to Asp11 bond, which acid and heat speed up. The BPC-157 stability page covers that route, freeze-thaw, light and what visible changes mean.
Solubility
BPC-157 is a hydrophilic, net negatively charged peptide at neutral pH, so it dissolves readily in bacteriostatic water without any acid. The BPC-157 solubility guide explains why, which concentrations dissolve cleanly and what causes haze.
Handling
Bench practice for BPC-157 is mostly about keeping the solution cold, clean and labelled. The BPC-157 handling page lists the steps and the common mistakes.
On arrival
What a sealed vial should look like, why it travels without an ice pack and where it goes first are on the BPC-157 on-arrival page.
Storage and reconstitution
Fridge and freezer windows, before and after mixing, are on how long BPC-157 lasts. Water volumes and the concentration table for a 10 mg vial are on how much bacteriostatic water for a BPC-157 10 mg vial.
FAQ
Short answers to the questions researchers ask most about storing, mixing and handling BPC-157 are on the BPC-157 FAQ.
Where to get it
Vistara Labs supplies BPC-157 10 mg as a lyophilised vial for laboratory research, shipped within Canada by Canada Post Xpresspost. A ready-mixed BPC-157 Nasal Spray and the BPC-157 + TB-500 blend are also available. More detail on sourcing is in Buy BPC-157 in Canada, and certificates are on our lab reports page.
All products supplied by Vistara Labs are intended for laboratory research use only. They are not drugs, are not approved for human or veterinary use, and are not intended to diagnose, treat, cure or prevent any condition. Nothing on this page constitutes medical advice or guidance for use in humans.
