Buy 5-Amino-1MQ in Canada: A Researcher's Guide

Buy 5-Amino-1MQ in Canada: A Researcher’s Guide

5-Amino-1MQ is not a peptide, it is a small-molecule NNMT inhibitor, and that distinction shapes how it is studied. It is studied for its effect on nicotinamide N-methyltransferase, an enzyme involved in how fat cells store and process energy. For Canadian researchers this guide covers what the compound is, what the laboratory research shows, how it is supplied and handled, and how ordering works within Canada.

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At a glance: Vistara Labs stocks 5-Amino-1MQ in 50 mg vials, independently tested, with a certificate of analysis on our Lab Reports page, shipped from within Canada by Canada Post Xpresspost, with same-business-day dispatch on orders before 3 pm Pacific. We deliver to every province, including Ontario, Quebec, British Columbia and Alberta.

What 5-Amino-1MQ is

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small synthetic molecule, far smaller than any peptide in the catalogue. It inhibits NNMT, an enzyme that is especially active in fat tissue, where it uses up nicotinamide by methylating it. Blocking NNMT leaves more nicotinamide available to the pathway that makes NAD+, which is why 5-Amino-1MQ is discussed alongside cellular-energy research. It is membrane-permeable, so it acts on an enzyme inside the cell rather than on a receptor at the cell surface. That is a different kind of job from the incretin peptides it is often grouped with, such as tirzepatide and retatrutide, which bind receptors and trigger a signalling cascade.

What the research covers

The published work is laboratory research. In diet-induced obese mice, NNMT inhibition with 5-Amino-1MQ reduced fat mass and body weight and protected against diet-driven weight gain without reducing food intake. Cell studies show the same inhibitor raising intracellular NAD+ in fat cells, and a later mouse study examined it in aged skeletal muscle and its stem cells. Current interest centres on NNMT as a link between how fat cells store energy and how much NAD+ the cell can make, a connection both lines of laboratory work support. The full picture is in our 5-Amino-1MQ research note.

How it is supplied

Vistara Labs stocks 5-Amino-1MQ in a 50 mg vial, supplied as a powder for laboratory research handling and third-party tested with the purity figure on the product page. It is also sold in packs of ten. Because 50 mg is a larger mass than a typical 10 mg peptide vial, the concentration after reconstitution is higher for the same volume of water: 5 mL of bacteriostatic water gives 10 mg/mL, and 2.5 mL gives 20 mg/mL. The volumes and syringe readings are set out in how much bacteriostatic water for a 5-Amino-1MQ 50 mg vial, and the peptide calculator handles any other combination.

Handling and storage

Keep the unopened vial cold, dry and away from light. After reconstitution with bacteriostatic water, label the vial with the date and concentration and store it refrigerated at 2 to 8 °C.

5-Amino-1MQ quality and lab reports

  • Purity documentation: certificates of analysis from independent laboratories are published for each compound on the Lab Results page, and the purity figure is listed on the product page.
  • Identity: the 5-amino-1-methylquinolinium cation has a molecular mass of about 159 Da, a fraction of the roughly 1,419 Da of a peptide such as BPC-157, which is why it is classed as a small molecule.
  • Mechanism: it inhibits NNMT inside the cell rather than binding a surface receptor, which places it in cellular-energy and NAD+ research.
  • Research-use framing: it is sold for laboratory research use only, with no medical claims.

Buying 5-Amino-1MQ in Canada

5-Amino-1MQ is not a controlled substance in Canada and is not an approved medicine; it is sold as a laboratory research material. Every order ships from within Canada, so there is no customs step. Questions about the compound or an order can go to our team at [email protected]. More detail is in are peptides legal in Canada? and domestic shipping within Canada.

Where it fits

5-Amino-1MQ sits with the metabolic compounds on the Weight Loss & Metabolism Research page, and its NAD+ connection links it to NAD+ research.

Frequently asked questions

Where can I buy 5-Amino-1MQ in Canada?

From domestic research suppliers. Vistara Labs stocks 5-Amino-1MQ and ships it from within Canada to every province.

Is 5-Amino-1MQ a peptide?

No. It is a small-molecule NNMT inhibitor, not a peptide, though it is often grouped with research peptides.

What has 5-Amino-1MQ research shown?

In diet-induced obese mice, 5-Amino-1MQ reduced fat mass and body weight without reducing food intake, and in fat cells it raised intracellular NAD+. The published work to date is laboratory research in cells and mice.

What concentration does a 50 mg vial give?

It depends on the water added: 10 mg/mL with 5 mL of bacteriostatic water, or 20 mg/mL with 2.5 mL.

Is 5-Amino-1MQ legal in Canada?

It is sold for laboratory research use only. It is not sold for human use, and nothing here is medical advice.

All products discussed are for laboratory research use only and are not for human use. Nothing on this page is medical advice, and no statement about any compound is a claim of therapeutic benefit.

References

5-Amino-1MQ is a small-molecule NNMT inhibitor rather than a peptide. No completed human clinical trial was identified; the research below is preclinical.

  1. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in miceNeelakantan H et al. · Biochem Pharmacol 2018 · PMC5826726Characterises 5-Amino-1MQ as a selective, cell-permeable NNMT inhibitor in laboratory studies. No human trial identified.

Links open the study record on PubMed so the source can be checked directly. Listing a study is not a claim that its findings apply to any other use, product or route of administration. Research use only.

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