Kisspeptin 10mg research vial

Buy Kisspeptin in Canada: Vial and Nasal Spray

You can buy kisspeptin in Canada from Vistara Labs in two formats: a 10 mg lyophilised vial and a ready-mixed nasal spray that holds 10 mg in 5 mL, about 28 sprays at 350 mcg per spray, both shipped from within Canada. Kisspeptin is the signal at the top of the reproductive hormone axis, and much of the human research on it comes from Imperial College London: an infusion raised LH, FSH and testosterone in men in 2005, a single injection triggered egg maturation during IVF in 2014, and infusions changed how the brain processed erotic videos in women and men with low sexual desire in 2022 and 2023. This guide covers both formats, the kisspeptin spray stack and what the studies found.

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At a glance: Vistara Labs stocks kisspeptin as a 10 mg vial and as a ready-mixed 10 mg nasal spray, independently tested at 99.8% purity, with a certificate of analysis on our Lab Reports page, shipped from within Canada by Canada Post Xpresspost, with same-business-day dispatch on orders placed before 3 pm Pacific, Monday to Friday. We deliver to every province, including Ontario, Quebec, British Columbia and Alberta.

Findings

  • Reproductive hormones, 2005: a 90-minute infusion of kisspeptin-54 raised LH, FSH and testosterone in men compared with saline, with mean LH of 10.8 vs 4.2 U/L (Journal of Clinical Endocrinology & Metabolism).
  • Kisspeptin-10, 2011: a single intravenous bolus raised LH from 4.1 to 12.4 IU/L at 30 minutes in healthy men, and a continuous infusion increased LH pulse frequency (Journal of Clinical Endocrinology & Metabolism).
  • Egg maturation, 2014: one injection of kisspeptin-54 induced egg maturation in women undergoing IVF, and embryos were transferred in 92% (49 of 53) of them (Journal of Clinical Investigation).
  • Brain responses, 2017: in 29 healthy young men, kisspeptin enhanced limbic brain activity specifically in response to sexual and couple-bonding images (Journal of Clinical Investigation).
  • Ready to use: the spray is pre-mixed in a sealed metered atomiser, about 350 mcg per spray, with nothing to reconstitute.

Which kisspeptin formats are there?

FormatWhat it holdsPreparation
Kisspeptin vial, 10 mg10 mg lyophilised powderReconstitute with bacteriostatic water
Kisspeptin Nasal Spray, 10 mg10 mg in 5 mL, about 28 sprays at 350 mcgReady-mixed, nothing to reconstitute
Libido Trifecta Spray StackKisspeptin, PT-141 and oxytocin spraysAll three ready-mixed

The spray arrives pre-mixed in sterile saline, so no bacteriostatic water is needed. Our table of sprays per bottle covers the sprays we stock.

Which spray stack includes kisspeptin?

The Libido Trifecta Spray Stack adds the 10 mg Kisspeptin Nasal Spray to the 10 mg PT-141 Nasal Spray and oxytocin nasal spray (2 mg or 10 mg) of our Libido Spray Stack, covering three pathways studied in libido research: the reproductive hormone axis, central melanocortin signalling and social bonding. See buying PT-141 in Canada and buying oxytocin nasal spray in Canada.

What is kisspeptin?

Kisspeptin is a naturally occurring peptide hormone encoded by the KISS1 gene. The gene was first described in 1996 by researchers at Penn State in Hershey, Pennsylvania, who found it expressed only in melanoma cells that did not spread. In 2001, peptides of 54, 14 and 13 amino acids sharing a common RF-amide end were isolated from human placenta, shown to activate the receptor GPR54 and named kisspeptins. Kisspeptin-10 is the minimal kisspeptin sequence with full intrinsic bioactivity, while kisspeptin-54 is the major circulating form in humans.

The reproductive role emerged in 2003, when mutations in GPR54 were found in people who had never gone through puberty (idiopathic hypogonadotropic hypogonadism). Kisspeptin acts upstream: through GnRH it prompts the pituitary to release LH and FSH, which drive sex hormone production. For the downstream end of the same axis, see buying HCG in Canada.

What has kisspeptin research shown?

  • Men, 2005. In a double-blind crossover study of 6 men, a 90-minute intravenous infusion of kisspeptin-54 significantly increased LH, FSH and testosterone compared with saline.
  • Women, 2007. Subcutaneous kisspeptin-54 raised LH in every phase of the menstrual cycle, with the greatest effect in the preovulatory phase: a mean rise of 20.64 IU/L over baseline.
  • Kisspeptin-10, 2011. In healthy men, a kisspeptin-10 infusion raised mean LH from 5.2 to 14.1 IU/L and LH pulse frequency from 0.7 to 1.0 pulses per hour.
  • IVF, 2014. In 53 women undergoing IVF, a single subcutaneous injection of kisspeptin-54 induced egg maturation; clinical pregnancy followed in 23% (12 of 53).
  • IVF at high risk of OHSS, 2015. In 60 women at high risk of ovarian hyperstimulation syndrome, egg maturation occurred in 95%, live birth per transfer was 45%, and no woman developed moderate, severe or critical OHSS.
  • Sexual and bonding images, 2017. In 29 healthy young men, kisspeptin enhanced limbic brain activity in response to sexual and couple-bonding images and attenuated negative mood.
  • Women with low sexual desire, 2022. In a placebo-controlled trial of 32 premenopausal women with hypoactive sexual desire disorder, kisspeptin modulated sexual and facial attraction brain processing, with no reported adverse effects.
  • Men with low sexual desire, 2023. In a placebo-controlled trial of 32 men with hypoactive sexual desire disorder, kisspeptin significantly modulated sexual brain processing and increased penile tumescence to sexual stimuli by up to 56% more than placebo.

These human studies gave kisspeptin by intravenous infusion or bolus, or by subcutaneous injection, not as a nasal spray. The spray is our ready-mixed laboratory format. Our overview of peptides in libido research covers the wider field.

Vial or spray?

The spray fixes the concentration and the amount per spray and is ready to use. The 10 mg vial is lyophilised and reconstituted with bacteriostatic water, which lets the researcher choose the concentration; our guide to reconstituting peptides and the peptide calculator cover the arithmetic.

How should kisspeptin be stored?

A peptide in solution is far less stable than the freeze-dried powder in a vial. Once opened, keep the spray in the fridge at 2 to 8 °C, upright, capped and away from light, never frozen, and follow the storage directions on its label. Our guide to storing a peptide nasal spray covers priming and handling.

Where to buy kisspeptin in Canada

  • No customs step. Every order ships from within Canada.
  • Same-day dispatch. Orders placed before 3 pm Pacific, Monday to Friday, leave the same business day by tracked Canada Post Xpresspost, with free Xpresspost on larger orders.
  • Tested. Kisspeptin is independently tested at 99.8% purity, with the certificate of analysis linked on both product pages.
  • Payment. We accept Interac e-Transfer, all major credit cards and crypto (Bitcoin).
  • All the sprays. See peptide nasal sprays in Canada.

Frequently asked questions

How much kisspeptin is in each spray?

About 350 mcg. The bottle holds 10 mg in 5 mL of sterile saline, about 28 sprays.

Does kisspeptin nasal spray need mixing?

No. It arrives pre-mixed in sterile saline in a sealed metered atomiser, ready to use.

What has kisspeptin research shown?

Kisspeptin raised LH, FSH and testosterone in men (2005), raised LH most strongly in the preovulatory phase in women (2007), triggered egg maturation during IVF (2014 and 2015), enhanced brain responses to sexual and couple-bonding images (2017) and modulated sexual brain processing in women (2022) and men (2023) with low sexual desire.

How was kisspeptin given in the human studies?

By intravenous infusion or bolus, or by subcutaneous injection. The nasal spray is our ready-mixed laboratory format.

Is there a spray stack with kisspeptin?

Yes. The Libido Trifecta Spray Stack combines the 10 mg Kisspeptin Nasal Spray with the 10 mg PT-141 Nasal Spray and an oxytocin nasal spray (2 mg or 10 mg).

Where can I buy kisspeptin in Canada?

Vistara Labs supplies kisspeptin as a 10 mg vial and a ready-mixed 10 mg nasal spray, shipped from within Canada by Canada Post Xpresspost.

Sources: Lee JH, et al. J Natl Cancer Inst. 1996. PMID 8944003. Kotani M, et al. J Biol Chem. 2001. PMID 11457843. Seminara SB, et al. N Engl J Med. 2003. PMID 14573733. Dhillo WS, et al. J Clin Endocrinol Metab. 2005. PMID 16174713. Dhillo WS, et al. J Clin Endocrinol Metab. 2007. PMID 17635940. George JT, et al. J Clin Endocrinol Metab. 2011. PMID 21632807. Jayasena CN, et al. J Clin Invest. 2014. PMID 25036713. Abbara A, et al. J Clin Endocrinol Metab. 2015. PMID 26192876. Comninos AN, et al. J Clin Invest. 2017. PMID 28112678. Thurston L, et al. JAMA Netw Open. 2022. PMID 36287566. Mills EG, et al. JAMA Netw Open. 2023. PMID 36735255.

More on this: Peptides for Women’s Libido: What PT-141 and Oxytocin Research Shows.

All products supplied by Vistara Labs are intended for laboratory research use only. They are not drugs, are not approved for human or veterinary use, and are not intended to diagnose, treat, cure or prevent any condition. Nothing on this page constitutes medical advice or guidance for use in humans.

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