Tesamorelin and Ipamorelin research vials

Buy the Tesamorelin + Ipamorelin Stack in Canada

You can buy the Tesamorelin + Ipamorelin Stack in Canada from Vistara Labs: one vial of 10mg Tesamorelin and one vial of 10mg Ipamorelin, packed as a pair and sent from within Canada. The two peptides meet at the growth-hormone axis but arrive there through different doors: tesamorelin binds the GHRH receptor, and Ipamorelin binds the ghrelin receptor. This guide covers what each vial holds, what the published work on each compound reports, why researchers place them side by side and how to order the tesamorelin ipamorelin stack Canada-wide.

Tesamorelin + Ipamorelin StackView product →

At a glance: This stack is two sealed lyophilised vials, 10mg Tesamorelin and 10mg Ipamorelin, kept separate rather than blended. Certificates of analysis for both compounds sit on our Lab Reports page. Every parcel goes from within Canada by Canada Post Xpresspost, and orders placed before 3 pm Pacific, Monday to Friday, leave the same business day. We deliver to every province, including Ontario, Quebec, British Columbia and Alberta.

Findings

  • 10mg Tesamorelin, stability: a trans-3-hexenoyl group fixed to its N terminus shields the DPP-4 cleavage site, the weak point that lets the enzyme dismantle native GHRH within minutes.
  • 10mg Ipamorelin, 1998: the first report described it as a selective secretagogue, matching GHRP-6 on growth hormone release with no rise in ACTH or cortisol beyond GHRH-like levels and an unchanged prolactin reading.

What is in the Tesamorelin + Ipamorelin Stack?

VialSizeResearch area
Tesamorelin10mgGHRH-receptor signalling
Ipamorelin10mgGhrelin-receptor signalling

Each peptide comes in its own vial as a freeze-dried powder. Keeping them apart, rather than combining them in a single pre-blended vial, means a researcher can prepare, label and track each compound independently.

What is tesamorelin?

Tesamorelin is a stabilised analogue of growth hormone releasing hormone, or GHRH. The natural hormone is a 44-amino-acid peptide with a very short half life, because dipeptidyl peptidase-4 (DPP-4) cuts it apart almost as soon as it is made. Tesamorelin answers that problem with a single chemical change: a trans-3-hexenoyl group on the N terminus that blocks the cut. The receptor target stays the same as native GHRH, while the time before degradation grows usefully longer.

That stability is also what separates it from sermorelin, another GHRH analogue that corresponds closely to the first 29 amino acids of the native hormone. Both reach the same receptor, so the difference researchers weigh is durability rather than target. Its certificate reports purity above 99 percent, measured by chromatography.

What is Ipamorelin?

Ipamorelin is a synthetic peptide only five amino acids long, derived from a series of compounds that remove the two central residues of GHRP-1, an earlier growth hormone releasing peptide. It acts on the ghrelin receptor, GHS-R1a, in the pituitary, prompting the gland to release its own growth hormone rather than supplying any hormone directly.

Its reputation rests on selectivity. Older relatives such as GHRP-6 and GHRP-2 pushed up the stress-hormone pair along with growth hormone, while Ipamorelin did not. Laboratory work has since followed several further threads:

  • Bone. Faster longitudinal bone growth and higher bone mineral content were reported in laboratory studies.
  • Glucocorticoid models. In one model, Ipamorelin counteracted the loss of muscle strength and bone formation that a glucocorticoid produced on its own.
  • Gut motility. In a model of postoperative ileus, it shortened the time before gut transit restarted after surgery.

Why are tesamorelin and Ipamorelin studied together?

Because they are not two versions of the same lever. Tesamorelin belongs with the GHRH analogues, the group that also includes sermorelin and CJC-1295. Ipamorelin belongs with the growth hormone secretagogues, which work through the ghrelin receptor instead. Two compounds can both be filed under the growth-hormone axis and still be doing mechanistically separate things, and that matters whenever a study is designed around one pathway.

Pairing one compound from each group lets a protocol examine both receptor inputs to the pituitary at once. The same logic explains why CJC-1295 and Ipamorelin are so often combined. Our comparison of CJC-1295 + Ipamorelin vs tesamorelin sets the two approaches out in detail.

How are the vials prepared?

Both vials are reconstituted with bacteriostatic water in the laboratory before use, and our walkthrough on how to reconstitute peptides with bacteriostatic water covers the method. Until then, unopened vials are best kept cold and away from light, and a reconstituted vial is labelled with its date and concentration.

Stack or single vials?

Where to buy the Tesamorelin + Ipamorelin Stack in Canada

  • Domestic parcel. Nothing crosses a border, so there is no customs step between our shelf and your laboratory.
  • Quick dispatch. Tracked Xpresspost leaves the same business day for orders in before 3 pm Pacific, Monday to Friday, and Xpresspost is free on larger orders.
  • Payment. We accept Interac e-Transfer, all major credit cards and crypto (Bitcoin).
  • The full range. All six vial stacks are compared in our guide to peptide stacks in Canada.

Frequently asked questions

What is in the Tesamorelin + Ipamorelin Stack?

Two separate lyophilised vials: 10mg Tesamorelin, a stabilised GHRH analogue, and 10mg Ipamorelin, a selective ghrelin-receptor agonist.

What has research on tesamorelin shown?

Tesamorelin keeps the receptor target of native GHRH, yet resists the DPP-4 enzyme that breaks the natural hormone down within minutes, thanks to a trans-3-hexenoyl cap at its N terminus.

What has research on Ipamorelin shown?

Introduced in 1998, Ipamorelin matched GHRP-6 for growth hormone release without lifting ACTH or cortisol above GHRH-like levels, and prolactin was unchanged. Laboratory studies also reported faster bone growth and higher bone mineral content.

How does the Tesamorelin + Ipamorelin Stack ship?

From within Canada by tracked Canada Post Xpresspost, leaving the same business day on orders placed before 3 pm Pacific, Monday to Friday.

More on this: our tesamorelin research note.

All products supplied by Vistara Labs are intended for laboratory research use only. They are not drugs, are not approved for human or veterinary use, and are not intended to diagnose, treat, cure or prevent any condition. Nothing on this page constitutes medical advice or guidance for use in humans.

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